The patented pheromone naturally calms dogs in stressful situations. It reduces anxiety in a new or stressful environment. Studies show that this pheromone mist modifies both the behaviors and physiology brought on by stress. Clinical testing revealed that the pheromone even reduced pets' elevated heart rates when exposed to noises and activities that create anxiety. It's an excellent choice for temporary stressful situations such as trips to the veterinarian, groomer or new visitors. It can also be used in the dog's crate or bed to comfort and calm them when you're not home. It helps make dogs feel secure and safe at home and on-the-go.